Before you receive Venofer, tell your doctor if you have low blood pressure, hepatitis, or if you have received many blood transfusions in the past. The information provided is not intended to replace your healthcare provider's medical advice. Venofer (iron sucrose) is given as an injection into the veins (intravenously or IV) by a trained healthcare provider. Once inside your body, ferric carboxymaltose releases iron into your system. Before taking Injectafer, be sure to tell your doctor or pharmacist about any medications you take, including any over-the-counter vitamins or supplements. Your doctor will do laboratory tests to monitor your response. If administering via IV infusion, up to 750 mg of Injectafer should be diluted in no more than 250 mL of sterile 0.9% sodium chloride solution (NaCl). As a result, you may not make as much EPO as usual. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If youre sexually active and you or your partner can become pregnant, talk with your doctor about your birth control needs while youre taking Injectafer. Its possible to get rid of or reduce the severity ofside effects. Be ready to tell or show what was taken, how much, and when it happened. * Feraheme has a boxed warning for this side effect. For this purpose, Injectafer is approved for use in adults who either: Venofer is also approved to treat IDA. Iron-refractory iron deficiency anemia (IRIDA) is a genetic form of anemia. They can tell you about other medications that may work well for you. 2. Instead, youll start by receiving just one treatment course of Injectafer. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Other drugs may interact with iron sucrose, including prescription and over-the-counter medicines, vitamins, and herbal products. What to Expect When You Get Your Whole Genome Sequenced, DNA Data Can Help You Understand Ehlers-Danlos Syndrome (EDS). endobj WARNINGS/CAUTIONS: Serious hypersensitivity reactions, including anaphylactic-type reactions (itching, hives, swelling, wheezing, difficulty breathing, fainting and/or other allergy symptoms), some of which have been life threatening and fatal, have happened in patients receiving Venofer. <> An example of a drug interaction that many people are not aware of isgrapefruitjuice and statins. Copyright 1996-2023 Cerner Multum, Inc. If you have a severe allergic reaction to Injectafer after youve left the medical facility where you received your dose of the drug, call your doctor right away. After 5 weeks of treatment: This study didnt determine if either drug was better than the other. Injectafer and Venofer have different approved uses, but theyre both used to treat IDA in people with CKD. Treatment with Venofer injections can make it harder for your body to absorb iron medications you take by mouth. Talk with your doctor. endobj Discuss the risks and benefits with your doctor. In the studies, peoples hemoglobin level was measured to check for improvement in their anemia. Learn about the causes, symptoms, diagnosis, and treatment of this. Dr. Colby holds an MD from the Mount Sinai School of Medicine, an MBA from Stanford Universitys Graduate School of Business, and a degree in Genetics with Honors from the University of Michigan. Tell your doctor if you are taking iron supplements or other iron-based oral medications, such as: This list is not complete. The following information describes dosages that are commonly used or recommended. So the goal of IDA treatment with Injectafer is to bring your hemoglobin level back to a value thats within normal range. These lists contain up to 10 of the most common mild side effects that can occur with Injectafer, with Venofer, or with both drugs (when taken individually). pain or burning at the injection site. There are different types of anemia, but IDA is the most common type. For people weighing less than 50 kg, administer Injectafer in two doses of 15 mg/kg of body weight, at least 7 days apart. Tell your doctor right away if you have any serious side effects, including: abdominal pain, chest pain, irregular heartbeat (arrhythmias), pressure in the chest, severe headache and blurred vision (hypertension), problems with your dialysis access site (graft). There may be drug take-back programs in your area. If you have iron deficiency anemia (IDA), consuming moderate amounts of alcohol may be safe, if your doctor tells you its OK. (With IDA, you have a low level of red blood cells thats caused by not having enough iron.). Hypophosphatemia has been reported in people using Injectafer after the drug was released onto the market. Common side effects of Venofer include: muscle cramps, nausea, vomiting, stomach pain, strange taste in the mouth or decreased sense of taste, diarrhea, constipation, headache, cough, sore throat, sinus pain, congestion, back pain, joint pain, dizziness, weakness, tired feeling, anxiety, ear pain, swelling of the arms/legs, or Laboratory tests (such as complete blood count, ferritin, transferrin, total iron binding capacity-TIBC) should be performed periodically to monitor your progress or check for side effects. It is important to get each dose of this medication as scheduled. How Viagra became a new 'tool' for young men, Ankylosing Spondylitis Pain: Fact or Fiction. But call 911 if your symptoms feel life threatening or if you think youre having a medical emergency. Allergic reaction As with most drugs, some people can have an allergic reaction after taking Injectafer. upper respiratory infection. Below are examples of these side effects. Also tell them about any vitamins, herbs, and supplements you use. This treatment course is split into two doses of the drug, which are given at least 7 days apart. Venofer (iron sucrose) is given by injection into a vein as directed by your doctor. Iron is important for many functions in the body, especially for the transport of oxygen in the blood. In clinical studies, people who took Injectafer had their hemoglobin level improve as early as 35 days after receiving treatment. In some cases, they may even recommend that you use a drug other than Injectafer to treat your anemia. What is Venofer? Can diet help improve depression symptoms? It can be given as a slow injection over 2 to 5 minutes or as an infusion. Amounts of iron ingested by the infant would be normal and are not expected to cause any adverse effects in breastfed infants. Hypophosphatemia seems to mostly occur in people who are already at risk for low phosphorus levels. Its not currently available in generic form. Injectafer is indicated to treat iron deficiency anemia (IDA) in adults who meet one of the following criteria: Injectafer is administered intravenously, either by intravenous (IV) infusion or as an undiluted, slow IV push. However, Injectafer has been studied for use in children with iron deficiency anemia (IDA). Effectiveness of Injectafer compared with iron thats taken by mouth. Call your doctor for instructions if you miss an appointment for your Venofer injection. A delayed reaction can occur in two different ways: It can happen hours or days after you receive a drug, or it can happen after a second (or later) dose of a drug. During Injectafer treatment, your doctor will likely order blood tests. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. If youre taking iron pills, be sure to tell your doctor before starting Injectafer. These effects typically last between 7 and 11 hours. Consult your doctor before breast-feeding. You will need to talk about the benefits and risks to you and the baby. I got Venofer twice in the last few years and now my iron deficiency is worse than ever, first time my hemoglobin is down to 11,2. But for other people, doing so could lead to having too much iron in their body. If you would like to report to the FDA a side effect youve had with Injectafer, you can do so through MedWatch. Review our medical disclaimer. (For more information on Venofer, see the Injectafer vs. Venofer section above). Its FDA-approved to treat iron deficiency anemia (IDA) in adults. (A generic drug is an exact copy of the active drug in a brand-name medication.) With IDA, you have low hemoglobin levels. Feraheme also comes as a liquid thats given by IV infusion. But its only approved for use in people with CKD who may or may not need dialysis. If this happens, you may need to get another treatment course of Injectafer, if your doctor recommends it for you. And this over-activation is what may lead to an allergic reaction or a delayed allergic reaction. People who are ongoingcancer treatmentwithradiation therapyor takingchemotherapy drugsmay be more susceptible toside effects. If your symptoms or health problems do not get better or if they become worse, call your doctor. fever. Examples of other drugs that may be used to treat IDA include: Your doctor will recommend the drug thats right for you depending on the severity of your anemia and any other medical conditions you may have. Grapefruitjuice may be healthy for people to drink, but it can cause someseriousside effects. Here we look at how Injectafer and Venofer are alike and different. With IV infusion, the drug is given as a slow drip into your vein over a period of time. Severeside effectscan lead to injury or death -drowsinesscan cause a car accident or injury when operating heavymachinery. Venofer may reduce the absorption of iron preparations taken by mouth. You may also need to monitor your blood pressure at home. There are 2 tests that your doctor will likely If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. What Is the Cost of Whole Genome Sequencing (WGS)? If you have questions about the best diet for you during Injectafer treatment, talk with your doctor. chest pain. These symptoms can include: While youre taking Injectafer, your doctor will monitor your phosphorus levels if youre at risk for hypophosphatemia. Only 10 mg may be excreted by the body the next time it goes through the liver, and possibly only 5 mg the nextpass. Use of the term female in this article refers to sex assigned at birth. Iron sucrose can harm an unborn baby if you have a severe reaction to this medicine during your second or third trimester. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. The iron released by this drug does pass into human breast milk. Some people only need one treatment course of Injectafer. Both Injectafer and Venofer belong to a class of medications called iron replacement products. fever. Side effectsare uncomfortable reactions to medications or drugs. The researchers found that compared with their hemoglobin level before the study: But the actual price youll pay for either drug depends on your insurance plan, your location, and the pharmacy you use. If you have any of these health problems: Too much iron in your body or anemia from a cause other than low iron. Injectafer and Venofer are both brand-name drugs. But for other people, their IDA returns after treatment with Injectafer. Pain, swelling, or redness at the injection site may occur. Details. The following lists contain some of the key side effects that may occur while taking Injectafer. Most mild side effects of Injectafer typically go away within about 30 minutes of receiving your dose of the drug. Venofer is for use in adults and children at least 2 years old. If you have questions about side effects, call your doctor. Without enough hemoglobin, the right amount of oxygen may not reach certain parts of your body. This way, if you have an allergic reaction to Injectafer, your healthcare professional can treat your reaction. Not all possible drug interactions are listed here. Check with your pharmacist if you have questions about the best way to throw out drugs. You should not receive Venofer if you have known allergies to iron sucrose. Innovators Monograph It is usually given slowly over 2 to 5 minutes or as directed by your doctor. Tell your caregivers right away if you have: problems with your dialysis vein access point; high blood pressure - severe headache, blurred vision, pounding in your neck or ears; low blood pressure - a light-headed feeling, like you might pass out; or. You can also write a reminder on your calendar. Common side effects may include: fever, cold or flu symptoms ( sore throat, cough, stuffy nose, sneezing); high or low blood pressure; headache, dizziness; nausea, vomiting; diarrhea; If you notice other effects not listed above, contact your doctor or pharmacist. Injectafer can be exposed to temperatures between 59F to 86F (15C to 30F) for a short period of time. <> Can poor sleep impact your weight loss goals? Last updated August 20, 2020. Some products that may interact with this drug include: vitamin products, other iron-containing products. "The most common side effects to COVID vaccines include pain at the injection site, fevers, chills, nausea, headaches, tiredness, and painful or swollen lymph nodes in the arm where the vaccine. Patients should induce vomiting or evacuate the stomach by lavage during Venofer overdoasge. (A class of medications describes a group of drugs that work in the same way.). fever, cold or flu symptoms (sore throat, cough, stuffy nose, sneezing); bruising or irritation where the medicine was injected. Many people using this medication do not have serious side effects. Your healthcare provider will watch you closely for 30 minutes after each dose. It belongs to a class of medications known as iron replacement products. You may also report side effects at https://www.fda.gov/medwatch. Your doctor may also recommend that you take iron supplements by mouth (if you havent tried these supplements in the past). For more information on the possible side effects of Injectafer, talk with your doctor or pharmacist. But if they become more severe or dont go away, talk with your doctor or pharmacist. And Feraheme is approved for use in adults who have CKD who may or may not need dialysis. You would receive 15 mg of Injectafer per kilogram of body weight for each of your two doses. It belongs to a class of medications called iron replacement products. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Potential injection site discoloration has happened. SIDE EFFECTS: Muscle cramps, nausea, vomiting, strange taste in the mouth, diarrhea, constipation, headache, cough, back pain, joint pain, dizziness, or swelling of the arms/legs may occur. Hemoglobin is a protein thats found inside your red blood cells. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Venofer. It depends. Reblozyl is a brand-name prescription medication used to treat anemia in certain blood disorders. But you kidneys need iron in order to make EPO. These include: Note: For more information about the potential negative effects of Injectafer, see the Injectafer side effects section above. In the second group, some people switched from taking iron by mouth to taking Injectafer. Click below for effective ways to alleviate the discomfort felt fromside effects and learn how to get a free Medication and Drug Reaction DNAReport. They have been a god send. 2 0 obj Learn more about these, as well as the symptoms, diagnosis, and treatments. IQVIA [NSP Audit from MAT November 2013 to November 2018]. Your body then uses the iron from Injectafer to make hemoglobin and new RBCs. . Injectafer contains the active drug ferric carboxymaltose, while Venofer contains the active drug iron sucrose. Venofer and the Venofer logo are registered trademarks of Vifor (International) Inc., Switzerland. The benefit of treating your condition during pregnancy may outweigh any risks. If you have questions about using Injectafer for anemia during pregnancy, talk with your doctor. If you have questions about side effects, call your doctor. This means that your doctor and insurance company will need to communicate about your prescription before the insurance company will cover the drug. Together, you and your doctor can discuss the benefits and risks of treatment options for anemia. If youre wondering how longside effectslast, youll be happy to know they can last just a few hours. If you need financial support to pay for Injectafer, or if you need help understanding your insurance coverage, help is available. Back pain. Examples of thisinclude: Not allside effectslast forever. But the length of time that this may take varies from person to person. These changes could help improve your anemia on a long-term basis. This information should not be used to decide whether or not to take Venofer or any other medicine. If youre not sure if youll need to get prior authorization for Injectafer, contact your insurance company. Call your doctor for medical advice about side effects. wAd**CgI%"nn{Oa[q{r5 Understanding what thoseside effectsare can lead to a strategy to prevent them. Its not known if Injectafer is safe to use during pregnancy. This medicine is sometimes given slowly, and the infusion can take up to 2.5 hours to complete. Others last much longer (even a lifetime), which can be quite traumatizing to people. Maximum concentrations of Injectafer are achieved within 15 minutes to 1.21 hours following administration. This is why family members often have the same issues with drugs as others in theirfamily. But for most people whove developed hypophosphatemia with Injectafer, the condition resolved within 3 months. Keep all medications away from children and pets. I had my first infusion of 1gm 10 days ago. Its given by either intravenous (IV) infusion or slow IV injection. Injectafer contains the active drug ferric carboxymaltose. Follow your doctor's directions carefully. People with IDA have low blood levels of hemoglobin. other treatments you receive, you will need to go back for several treatments with Venofer. Symptoms of overdosage include drowsiness, mental confusion, dizziness, diarrhea and vomiting etc. No, you dont need to follow a specific diet plan while youre using Injectafer unless your doctor recommends otherwise. Venofer is manufactured under license from Vifor (International) Inc., Switzerland. The time it takes to infuse Venofer (iron sucrose) depends on your age, if you're on dialysis, and the type of dialysis you need. Brand-name medications usually cost more than generics. But for other people, their anemia may come back after Injectafer treatment. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. Someside effectsare temporary or last as long as the person continues takingprescription medicine. This can be very helpful in . You may wonder how Injectafer compares with other medications that are prescribed for similar uses. Knowing how longside effectslast can help with the decision on whether to use a particulardrug. So theres no recommended pediatric dosage for Injectafer. (Hemoglobin is a protein thats found inside your red blood cells.). * This is a partial list of mild side effects from Injectafer. In the study, peoples hemoglobin level was measured to check for improvement in their anemia. Together, they can recommend ways to help you manage a body weight thats healthy for you. The Role of Genetics in Multifactorial Disorders, The Power of DNA Testing and Predictive Medicine, A Guide to Genome Explorer (Free Version), Whole Genome Sequencing in As Little As Three Weeks, What Diseases Can Be Detected Through Genetic Testing, Breast Cancer Genetic Testing: Pros and Cons, At Home Genetic Testing for Breast Cancer, DNA Tests for Breast Cancer Genetic Testing, What to Do When Medicines Have Side Effects, Blood Type and COVID: Infection Risk and Severity, Where Can I Get My Blood Type Checked for Free, How to Find Biological Father Through DNA. SIDE EFFECTS: In adult patients, the most common side effects (2%) include diarrhea, upset stomach, throwing up, headache, dizziness, hypotension, pruritus (itching), pain in extremity, arthralgia (joint pain), back pain, muscle cramp, injection site reactions, chest pain and peripheral edema (swelling). In the US - Call your doctor for medical advice about side effects. monitor along with your hemoglobin and red blood cell count: The Venofer patient brochure provides information and support for CKD patients (2 years and older) with IDA. Following an LSD trip, users may experience a sort of 'comedown.'. dizziness. Properly discard this product when it is expired or no longer needed. Typical Injectafer doses for iron deficiency anemia (IDA) depends on your body weight. Many people believe they are suffering fromside effectsand may actually be suffering from anothermedical condition, such as havingdifficulty breathingorshortness of breath, which could be a heartattack. Tell all of your health care providers that you take Venofer. Daiichi Sankyo, Inc., the manufacturer of Injectafer, offers a program called injectconnect, which may help lower the cost of the drug. These tests will help make sure Injectafer is working to treat your iron deficiency anemia (IDA). You will need frequent medical tests to help your doctor determine how long to treat you with Venofer. This information is not specific medical advice and does not replace information you receive from the healthcare provider. What is the latest research on the form of cancer Jimmy Carter has? Venofer (iron sucrose injection, USP) is indicated for the treatment of iron deficiency anemia (IDA) in adult and pediatric (2 years of age and older) patients with chronic kidney disease (CKD), and is administered only by or under the supervision of your healthcare provider. In pediatric patients the most common side effects (>2%) are headache, viral respiratory tract infection, peritonitis, upset stomach, throwing up, fever, dizziness, cough, arteriovenous fistula thrombosis, hypotension and hypertension (increased blood pressure). The potential side effects of Daxxify are nearly identical to that of Botox bruising, headaches, and droopy eyelids with one big difference: They could last longer. The infusion will take between 15-30 minutes if it is given in. Do not start, stop, or change the dose of any drug without checking with your doctor. Here we look at how Injectafer and Feraheme are alike and different. Do not use Injectafer in people with a history of hypersensitivity reactions to Injectafer or any components of the drug product. There are currently no generic forms of either drug. In this study, compared with their level before treatment: Injectafer isnt currently approved for use in children. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. . Symptoms of a severe allergic reaction can include: Because of the risk of allergic reaction with Injectafer, your healthcare professional will monitor you for at least 30 minutes after you get each dose of the drug. If you miss an appointment for your Injectafer dose, youll need to call your doctors office. This gives a total cumulative dose of 1,500 mg of Injectafer. Venofer Side Effects. FG Trade/E+ sia Getty Images Back pain. They can recommend appropriate treatment options. And this could lead to weight gain, if they increase their food intake. I can't take oral supplements because they cause horrible debilitating Constipation. These pregnancy-related problems include preterm delivery and low birth weight of your infant. A shortage of iron can cause health problems. All rights reserved. Is the ketogenic diet right for autoimmune conditions? Venofer is indicated to treat iron deficiency anemia (IDA) in adult and pediatric patients (2 years and older) with chronic kidney disease (CKD). Iron infusions are given directly into a vein. Medically reviewed by Sanjai Sinha, MD. However, side effects at the 150 mg dose may indicate that you might not . Side effects: DayQuil can cause side effects such as drowsiness, dizziness, nausea, vomiting, and stomach upset. 2022 American Regent, Inc.PP-VE-US-0016 (v6.0)1/2022, Iron is also necessary for your bone marrow to build healthy new red blood cells and provide oxygen to your organs and tissues through hemoglobin, If you or your child has been prescribed Venofer, its based on your blood work, which shows how many red blood cells you have and whether you have enough iron in your blood cells, If you are iron deficient, raising your iron levels can help increase your hemoglobin levels, Treating your anemia may help prevent future health problems, Over time, untreated IDA can cause heart problems; if you already have heart problems, it can make those problems worse, Venofer is given intravenously (through an IV) and Generic name: iron sucrose (injection) [EYE-urn-SOO-krose] chills difficulty with moving ear congestion or pain flushed, dry skin fruit-like breath odor increased hunger or thirst increased urination lack or loss of strength pain or redness at the injection site pale skin at the injection site runny nose, sneezing sore throat unexplained weight loss Rare Burning, dry, or itching eyes Nose or throat irritation. It's a more immediate treatment than supplements or dietary changes. The oral form of the drug, called sucroferric oxyhydroxide and used . Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. It can also cause skin irritation and redness. These side effects can range from being mild to severe. An iron infusion is a way to increase the body's iron levels quickly. People from different ethnic backgrounds process medications differently. To make sure Venofer injection is safe for you, tell your doctor if you have: hemochromatosis or iron overload (the buildup of excess iron). signs of inflammation in the lining of your stomach - pain or swelling, bloating, nausea, vomiting, loss of appetite, diarrhea, fever. fluid retention, especially in your arms, legs, or feet, people who took Feraheme had their hemoglobin level increase, on average, by 1.38 grams per deciliter (g/dL), people who took ferric carboxymaltose had their hemoglobin level increase, on average, by 1.63 g/dL, having strange cravings to eat items that arent food, such as ice, people who took Injectafer had their hemoglobin level increase, on average, by 1.6 grams per deciliter (g/dL), people who kept taking iron by mouth had their hemoglobin level increase, on average, by 0.8 g/dL, people who took Injectafer had their hemoglobin level increase, on average, by 2.9 g/dL, people who took the other intravenous iron product had their hemoglobin level increase, on average, by 2.2 g/dL, people who took Injectafer had their hemoglobin level increase by an average of 1.1 g/dL, people who took Venofer had their hemoglobin level increase by an average of 0.9 g/dL, cannot tolerate or have shown a poor response to oral iron, or, have been diagnosed with chronic kidney disease (CKD) that is non-dialysis dependent.
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